J. Ricardo Arias-Gonzalez received both his Master Degree in Theoretical Physics in 1997 and his Ph.D. in 2002 from Complutense University in Madrid. During his Ph.D. research in the Materials Science Insti- tute (ICMM-CSIC), Madrid, and short stays in the National Institute of Standards and Technology (NIST, Gaithersburg, MD), EMBL-Heidelberg and École Centrale Paris, he developed theory and simulations to understand the electromagnetic field in nanoparticles. Then, he moved to U.C. Berkeley for his postdoc- toral training, where he studied DNA with single molecule approaches. In 2006, he joined the National Centre of Biotechnology (CNB-CSIC), Madrid, where he developed a state-of-the-art optical tweezers and a subsequent experimental environment for single-molecule Biophysics. Since 2008, he has been working in IMDEA Nanoscience, leading of the Optical Nanomanipulation Lab.